Active Clinical Trials at OOS

All Clinical Trials

ARTEMIDE-Lung02 (D702BC00001)

Tumor site:
Lung
Description:
A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination with Platinum-based Chemotherapy for the First-line Treatment of Patients with Metastatic Squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1
Available at:
Notes:
Sponsor: AstraZeneca; NCT Number: NCT06692738

ARTEMIDE-Lung03 (D702FC00001)

Tumor site:
Lung
Description:
A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination with Platinum-based Chemotherapy for the First-line Treatment of Patients with Metastatic Non-squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1
Available at:
Notes:
Sponsor: AstraZeneca; NCT Number: NCT06627647

ASTX030-01

Tumor site:
Hematologic (MDS, CMML, AML)
Description:
A Multi-phase, Dose-Escalation followed by an Open-label, Randomized, Crossover Study of Oral ASTX030 (Cedazuridine and Azacitidine Given in Combination) Versus Subcutaneous Azacitidine in Subjects with Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML)
Available at:
Notes:
Sponsor: Astex; NCT Number: NCT04256317

B Stronger I (01-PS-001)

Tumor site:
Breast
Description:
Breast Cancer-Minimal/Molecular Residual Disease Detection and Therapy Monitoring in Patients with Early Stage TNBC-Phase I (B-STRONGER-I)
Notes:
Sponsor: Personalis; NCT Number: NCT06230185

BillionToOne (NS-002)

Tumor site:
Solid Tumors
Description:
Tumor methylation scores will be quantified at baseline across all tumor types to establish the clinical limit of detection of the assay. Associations between baseline tumor methylation score and PFS, OS, and disease control rate will be examined across therapeutic regimens and cancer types to test the hypothesis that the TMS is prognostic of outcome.
Notes:
Study Sponsor: BillionToOne Inc.; IRB number: 20231272
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