Active Clinical Trials at OOS

All Clinical Trials

AbbVie (M23-362)

Tumor site:
Hematologic (MDS, CMML, AML)
Description:
**Enrollment Closed** A Phase 2, Open-Label Trial to Evaluate Safety of Epcoritamab Monotherapy in Subjects with Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Classic Follicular Lymphoma (Previously Grade 1-3a) when Administered in the Outpatient Setting
Available at:
Our Salem Office
Notes:
Sponsor: AbbVie; NCT Number: NCT05451810

ARTEMIDE-Lung02 (D702BC00001)

Tumor site:
Lung
Description:
A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination with Platinum-based Chemotherapy for the First-line Treatment of Patients with Metastatic Squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: AstraZeneca; NCT Number: NCT06692738

ARTEMIDE-Lung03 (D702FC00001)

Tumor site:
Lung
Description:
A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination with Platinum-based Chemotherapy for the First-line Treatment of Patients with Metastatic Non-squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: AstraZeneca; NCT Number: NCT06627647

ASTX030-01

Tumor site:
Hematologic (MDS, CMML, AML)
Description:
A Multi-phase, Dose-Escalation followed by an Open-label, Randomized, Crossover Study of Oral ASTX030 (Cedazuridine and Azacitidine Given in Combination) Versus Subcutaneous Azacitidine in Subjects with Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML)
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: Astex; NCT Number: NCT04256317

Amplitude (67652000PCR3002)

Tumor site:
Prostate
Description:
***Enrollment closed*** A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants with Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: Janssen; NCT Number: NCT04497844

B Stronger I (01-PS-001)

Tumor site:
Breast
Description:
Breast Cancer-Minimal/Molecular Residual Disease Detection and Therapy Monitoring in Patients with Early Stage TNBC-Phase I (B-STRONGER-I)
Available at:
Our Salem Office, Our McMinnville Office, Our Silverton Office, Our Woodburn Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: Personalis; NCT Number: NCT06230185

AVANZAR (D926NC00001)

Tumor site:
Lung
Description:
**Enrollment Closed** A Phase III, Randomized, Open-label, Multicentre, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin Versus Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic NSCLC Without Actionable Genomic Alterations
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: AstraZeneca; NCT Number: NCT05687266

BDX-00146

Tumor site:
Lung
Description:
**Enrollment Closed** An Observational Study Assessing the Clinical Effectiveness of the VeriStrat® Test and Validating Immunotherapy Tests in Subjects with Non-Small Cell Lung Cancer (INSIGHT)
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: Biodesix Inc; NCT Number: NCT03289780

BillionToOne (NS-001)

Tumor site:
Solid Tumors
Description:
**Enrollment Closed** Compare the clinical relevant biomarkers identified by a novel BillionToOne quantitative ctDNA somatic mutation profiling assay with clinically available comparable assays in patients with advanced stage solid tumors.
Available at:
Our Salem Office
Notes:
Study Sponsor: BillionToOne Inc.; IRB number: 20230250

BillionToOne (NS-002)

Tumor site:
Solid Tumors
Description:
Tumor methylation scores will be quantified at baseline across all tumor types to establish the clinical limit of detection of the assay. Associations between baseline tumor methylation score and PFS, OS, and disease control rate will be examined across therapeutic regimens and cancer types to test the hypothesis that the TMS is prognostic of outcome.
Available at:
Our Salem Office, Our McMinnville Office, Our Silverton Office, Our Woodburn Office
Notes:
Study Sponsor: BillionToOne Inc.; IRB number: 20231272

Furmo (Furmo-004)

Tumor site:
Lung
Description:
**Enrollment Closed** A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Investigate the Efficacy and Safety of Furmonertinib Compared to Platinum-Based Chemotherapy as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT)
Available at:
Our Salem Office
Notes:
Sponsor:ArriVent BioPharma, Inc.; NCT Number: 05607550

G000 (BB-1701-G000-205)

Tumor site:
Breast
Description:
**Enrollment Closed** An Open-label, Multicenter, Phase 2 Dose Optimization and Expansion Study to Evaluate the Safety and Efficacy of BB-1701, an anti-human epidermal growth factor receptor 2 (anti-HER2) antibody-drug conjugate (ADC), in Previously Treated Subjects with HER2-positive or HER2-low Unresectable or Metastatic Breast Cancer
Available at:
Our Salem Office
Notes:
Sponsor: Eisai Inc.; NCT Number: NCT06188559

GEMINI

Tumor site:
Lung
Description:
TEMPUS GEMINI (TP-CA-002) NSCLC SURVEILLANCE STUDY: A Longitudinal Multi-Omic Biomarker Profiling Study of Patients with Non-Small Cell Lung Cancer (NSCLC)
Available at:
Our Salem Office, Our McMinnville Office, Our Silverton Office, Our Woodburn Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: Tempus; IRB Number: NCT05236114

INTRINSIC

Tumor site:
Colorectal Cancer
Description:
A Phase I/Ib global, multicenter, open-label umbrella study evaluating the safety and efficacy of targeted therapies in subpopulations of patients with metastatic colorectal cancer
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: Roche; NCT Number: NCT04929223

Mirati KRYSTAL 7

Tumor site:
Lung (NSCLC)
Description:
Phase 3 Trial of MRTX849 Plus Pembrolizumab for NSCLC With KRAS G12C Mutation (KRYSTAL-7)
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: Mirati Therapeutics Inc; NCT Numer: NCT04613596

Ovation-23-001

Tumor site:
Breast; Lung
Description:
Collection of Biological Specimens and Associated Health Information for Secondary Research in Future Studies
Available at:
Our Salem Office, Our McMinnville Office, Our Silverton Office, Our Woodburn Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Ovation.io, Inc. NCT# NCT06369441

VIKTORIA-1

Tumor site:
Breast
Description:
A Phase 3, Open-Label, Randomized, Two-Part Study Comparing Gedatolisib in Combination with Palbociclib and Fulvestrant to Standard-of-Care Therapies in Patients with HR-Positive, HER2-Negative Advanced Breast Cancer Previously Treated with a CDK4/6 Inhibitor in Combination with Non-Steroidal Aromatase Inhibitor Therapy
Available at:
Our Salem Office
More info:
See this trial on ClinicalTrials.gov »
Notes:
Sponsor: Celcuity; NCT Number: NCT05501886
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